Table 1. Experimental conditions utilized in the microarray studies.
Treatment Name (N) | Treatment Description |
T0 (3) | No treatment, time 0 control |
PBS 6 hr (4) | PBS-exposed, harvested at 6 hr |
PBS 24 hr (4) | PBS-exposed, harvested at 24 hr |
AZT 6 hr (3) | AZT-treated, harvested at 6 hr |
AZT 24 hr (4) | AZT-treated, harvested at 24 hr |
AZT 48 hr (3) | AZT-treated, harvested at 48 hr |
SMM 6 hr (4) | SMM-exposed, harvested at 6 hr |
SMM 24 hr (3) | SMM-exposed, harvested at 24 hr |
AZT 48 hr+SMM 6 hr (3) | AZT-treated for 48 hr; SMM-exposed during last 6 hrs |
AZT 72 hr+SMM 24 hr (3) | AZT-treated for 72 hr; SMM-exposed during last 24 hrs |
PBS: 30 µl mucosal phosphate-buffered saline; AZT: 30 µg/ml serosal azithromycin. SMM: 30 µl mucosal supernatant from mucopurulent material from CF airways. N = number of arrays from 4 different human HBE codes that were used for subsequent analyzes.