Figure 4.

(A) Binding of DiO-labeled OxLDL lipid microemulsions to mouse macrophages in the presence of liposomes containing PAPC (■) or oxidized PAPC (●). Elicited mouse macrophages were incubated in the presence of 10 μg/ml DiO-labeled OxLDL lipid microemulsions and PAPC-containing liposomes for 2 h at 4°C. Binding was quantitated as described for Fig. 1. (B) Binding of ¹²⁵I-apoB from OxLDL to mouse macrophages in the presence of liposomes containing PAPC (■) or oxidized PAPC (●). Elicited mouse macrophages were incubated with PAPC liposomes for 1.5 h at 4°C. After being washed to remove the unbound lipids, the cells were then incubated with 4 μg/ml of ¹²⁵I-OxApoB for an additional 1.5 h at 4°C. Binding was quantitated as described for Fig. 2.