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. 2009 May 15;5(5):e1000477. doi: 10.1371/journal.pgen.1000477

Figure 3. Power for Common versus Rare alleles.

Figure 3

Plots of power (solid lines) and coverage (dotted line) for increasing sample sizes of cases and controls (x-axis). From left to right plots are given for increasing effect sizes (relative risk per allele). Both power and coverage range from 0 to 1 and are given on the y-axis. Results are for single-marker test of association. The top two rows show the power for rare risk alleles (RAF<0.1) and the bottom two rows show the power for common risk alleles (RAF>0.1). Rows 1 and 3 show power for case-control studies simulated in a Caucasian population based on the CEU HapMap panel. Rows 2 and 4 relate to case-control studies simulated from the YRI HapMap panel.