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. Author manuscript; available in PMC: 2009 May 29.
Published in final edited form as: Microvasc Res. 2005 Aug 31;70(1-2):116–120. doi: 10.1016/j.mvr.2005.07.003

Fig. 3.

Fig. 3

Targeting NG2 proteoglycan on neovascular pericytes reduces interstitial hypertension in skin melanoma in mice. IFP measurements were performed 2 weeks following subcutaneous tumor grafting. Intrinsic (genetic) inhibition of NG2 proteoglycan decreases IFP in B16F1 melanoma grafts in NG2 knockout mice (average core IFP of −0.4 cm H2O) compared to B16F1 melanoma grafts in wild type controls[C0](average core IFP of +4.9 cm H2O) (n = 24, P = 0.0054 Mann–Whitney U test).