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. 2009 May 11;8:1. doi: 10.1186/1476-5926-8-1

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Copyright © 2009 Marek et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Screening for inhibitors of trans-differentiation in rat and human HSCs – Part 2. Photomicrographs of human HSCs at day 12 of culture with the indicated treatment (a); levels of expression of α-smooth muscle actin (α-sma) (b) and levels of expression of fibrogenic marker mRNA transcripts in human HSCs after treatment selected compounds for 19 days. Data are the mean and standard deviation relative transcript level from 3 separate treatments on cells from the same donor, typical of at least 3 separate donors (c).