Table 3.
Of 115 different Molecular Functions identified in the Gene Ontology analysis, 16 differed significantly in expression between normalized and native libraries.
Molecular Function | Total counts normalized | % of counts | Total counts native | % of counts | P-value |
actin binding | 7 | 1.13 | 24 | 0.30 | * |
ATP binding | 101 | 16.29 | 152 | 1.88 | *** |
cytochrome c oxidase | 78 | 12.58 | 155 | 1.92 | *** |
DNA binding | 23 | 3.71 | 76 | 0.94 | *** |
GTP binding | 6 | 0.97 | 22 | 0.27 | * |
isomerase activity | 4 | 0.65 | 8 | 0.10 | ** |
kinase activity | 4 | 0.65 | 5 | 0.06 | ** |
motor activity | 4 | 0.65 | 0 | 0.00 | *** |
oxygen binding | 12 | 1.94 | 2 | 0.02 | *** |
protein binding | 178 | 28.71 | 1348 | 16.71 | ** |
ribosome biogenesis | 0 | 0.00 | 811 | 10.05 | *** |
RNA binding | 33 | 5.32 | 1482 | 18.37 | *** |
structural constituent of ribosome | 0 | 0.00 | 1791 | 22.20 | *** |
sugar binding | 2 | 0.32 | 6 | 0.07 | ** |
ubiquinol-cytochrome-c reductase activity | 22 | 3.55 | 6 | 0.07 | *** |
zinc ion binding | 136 | 21.94 | 725 | 8.99 | *** |
P-value significance; * = 0.05, ** = 0.01, *** = 0.001.