Figure 3.

Aberrant spindle assembly and chromosome segregation in asun spermatocytes. Meiotic cells stained for α-tubulin (green in A1–D1; grayscale in A2–D2), centrosomes (γ-tubulin; red), and DNA (blue). Wild-type primary (A) and secondary (B) spermatocytes in telophase segregate DNA equally to daughter cells. (C and D) Representative asun primary spermatocytes. (C) Unequal segregation of DNA masses to three poles of a tetrapolar spindle. (D) Two spindles sharing a pole (arrowhead). Bar, 10 μm.