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. 2009 Jul 1;24(7):1297–1306. doi: 10.1007/s00467-008-0787-0

Table 1.

Summary of recent studies assessing final height in pediatric renal transplant recipients

Study Tx period Population (n) rhGH post-Tx (n) Age at Tx (years) Follow-up (years) Height SDSa Growth determinants
At Tx Final Height Normal heightb
Andre et al. 2003 [5] 1975 19 (11 boys) 0 13.2 10.9 −3.1 −2.6 42% Height at ESRD; duration and cause of ESRD
Englund et al. 2003 [6] 1981–1994 24 (8 boys) 6 9.5 7.6 −1.7 −1.1 75% Height at Tx; bone age; graft function
Ninik et al. 2002 [7] 1985–1998 82 (53 boys) 0 10.3 > 5 −2.1 (n = 82) −1.3 (n = 47) - Height at Tx; age at Tx; final GFR; steroid dose
Nissel et al. 2004 [8] 1983–2002 37 (18 boys) 0 10.2 (girls) 8.5 −2.9 (girls) −1.9 (girls) 68% Height at Tx; graft function
12.5 (boys) −1.7 (boys) −1.0 (boys)
Offner et al. 1999 [9] 1970–1993 100 (47 boys) 7 13.6 13.1 −2.2 −2.4c 47%c -
Rodriguez-Soriano et al. 2000 [10] 1986–1999 32 (17 boys) 3 12.1 7.2 (median) −1.6 (girls) −1.2 (girls) 69% Height at Tx and at start of dialysis; duration of dialysis
−1.4 (boys) −1.6 (boys)

Tx Transplantation, ESRD end stage renal disease, GFR glomerular filtration rate, SDS standard deviation score, rhGH recombinant human growth hormone

aHeight values are expressed in SDS compared with local measurements

bNormal height is defined as a final height > − 2 SDS

cFinal height in 84 non-cystinotic patients: −1.8 SDS (56% achieved normal height)