Table 2.
| Causes of growth impairment | Methods |
|---|---|
| Reduced GFR | Prevention and management of chronic allograft nephropathy |
| Treatment of acute rejection episodes | |
| Drug compliance | |
| Steroid therapy | Daily low or alternate day steroid therapy |
| Steroid avoidance/withdrawal under evaluation | |
| Bone disease | Target PTH within normal range in CKD stage 2–3 and < 2× upper limit in CKD stage 4 |
| Target plasma phosphate within age-appropriate normal range | |
| Metabolic acidosis | Target plasma bicarbonate > 22 mmol/L |
| Malnutrition | Adequate nutritional intake |
| Comorbidities | Assessment and control of comorbidities which may impair growth (chronic inflammation, liver, lung or heart diseases) |
PTH Parathyroid hormone; CKD chronic kidney disease