Table 3.

Summary of randomized controlled trials of rhGH therapy in children after renal transplantation

Study	Design	Population	Growth velocity (cm/year)		Safety
			rhGH group	Controls	Rejections	GFR
Hokken-Koleaga et al. 1996 [67]	6-months crossover	n = 11			No episode	No change
		5 prepubertal	3.9 (6 months)	1.0
		6 pubertal	5.3	1.5
Maxwell et al. 1998 [68]	1-year randomized	n = 22			8/13 in rhGH group vs. 5/9 in controlsa	No change
		15 prepubertal	8.1	3.7
		7 pubertal	10.1	3.9
Guest et al. 1998 [69]	1-year randomized	n = 90	7.7	4.6	9/44 in rhGH group vs. 4/46 in controlsa	No change
		55 prepubertal
		35 pubertal
Fine et al. 2002 [70]	1-year randomized	n = 63	9.0	4.2	None in rhGH group vs. 3 in controls	No change in SCrb
		40 prepubertal
		23 pubertal

^aNot significant

^bSCr, Serum creatinine