Table 3.

Image analysis evaluation (%)

Range	First sample (no.)	Second sample (no.)	P	Range	First sample (no.)	Second sample (no.)	P
Topoisomerase I
0	0	0	1	36–40	3	0	0.2405
1–5	21	1	0.0001	41–45	1	1	1.000
6–10	4	0	0.1156	46–50	1	1	1.000
11–15	2	4	0.6752	51–55	2	4	0.6752
16–20	3	5	0.7119	56–60	0	4	0.1156
21–25	2	3	1	61–65	0	5	0.0547
26–30	1	9	0.0143	66–70	0	0
31–35	0	3	0.2405	71–80	0	0
Topoisomerase IIa
0	0	0	1	36–40	2	3	1
1–5	10	4	0.1395	41–45	5	1	0.2007
6–10	6	5	1	46–50	0	3	0.2405
11–15	5	2	0.4315	51–55	0	2	0.4937
16–20	9	1	0.0143	56–60	0	0	1
21–25	0	5	0.0547	61–65	0	1	1
26–30	3	3	1	66–70	0	2	0.4937
31–35	0	3	0.2405	71–80	0	5	0.0547

Total	First determination			Second determination			P
	Mean	Median	Range	Mean	Median	Range
Topoisomerase I	13.875	4.5	1–54	35.375	29.5	4–65	0.0001
Topoisomerase IIa	16.775	15	1–45	34.575	31	2–79	0.0001