Figure 6.
NO2Tyr induces barrier dysfunction in A549 epithelial cells. Barrier function was assessed by the permeability of confluent cells to [125I]BSA as described in Methods. The percentage of NO2Tyr relative to tyrosine in the medium was 0%, 12%, 25%, 62%, 125%, 187%, and 250%. Values are expressed as the percentage of increase over control cells (basal medium) and represent the mean ± SD of four separate experiments.
