Table 1. Metabolic parameters of HFD WT and Cnr2 −/− mice.

	HFD WT	HFD Cnr2 −/−
Metabolism
Food intake (g/day)	2.6±0.00	2.7±0.1
Adiposity index (% of body weight)	9.6±0.4	6.8±0.8**
Adipocyte size (µm2)	9,937±391	6,166±1,009*
Metabolic rate (W)
Basal	0.31±0.02	0.30±0.00
Total	0.44±0.02	0.42±0.02
Spontaneous locomotor activity (kJ/g)	0.14±0.01	0.14±0.00
RQ (peak post meal)	0.92±0.02	0.85±0.01*
Fecal lipid (% of dry fecal weight)	19.9±1.5	25.9±3.1*
Cnr1 expression
Brain	1.02±0.01	1.42±0.30
Liver	1.21±0.33	0.43±0.06*
Adipose tissue	1.04±0.07	0.49±0.08***
Adipokines
Leptin (µg/L)	61±7	19±5***
Adiponectin (mg/L)	11.5±0.6	11.2±0.18

^*p<0.05 vs HFD WT.

^**p<0.01 vs HFD WT.

^***p<0.001 vs HFD WT.