Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Copper inhibits branched-chain biosynthesis even in the absence of oxygen. (A and B) E. coli cultures were grown anaerobically in glucose medium supplemented with either 1.5 mM alanine (ala) (squares) or 0.5 mM each of isoleucine (I), leucine (L), and valine (V) (circles), and they were then challenged with 0 μM (open symbols) or 2 μM CuSO4 (closed symbols). (A) W3110 (WT). (B) LEM33 (copA cueO cusCFBA). The data are representative of 3 independent experiments.
