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Inactivation of gyrA gene in E. coli [50 μM PPMO-EGS each: 4 hr after administration (LB broth)]
| PPMO-EGS | Colony counts | Fraction of survival |
|---|---|---|
| Control | 2.3 × 105 | 1.0 |
| Scrambled | 2.2 × 105 | 0.96 |
| EGS241 | 1.7 × 105 | 0.74 |
| PrEGS313 | 6.8 × 104 | 0.29 |
| 241 + 313 | 8.3 × 103 | 0.036 |
See legend for Table 3.
