Table 3.

Multivariable regression models searching for independent correlates of Ln (CAC+1)

	Model Without Interaction			Nested Interaction Model
Independent Variable	β	SE of β	P-value	β	SE of β	P-value
Age (years)	0.06	0.02	< 0.01	0.06	0.02	< 0.01
Non-Hispanic whites (vs. others)	0.44	0.30	0.15	0.45	0.30	0.14
Diabetes duration (years)	0.02	0.02	0.33	0.02	0.02	0.37
Hypertension (yes/no)	0.81	0.34	0.02	0.86	0.33	0.01
HbA1c (%)	−0.15	0.10	0.16	−0.16	0.10	0.13
Statin use (yes/no)	0.27	0.28	0.34	0.07	0.28	0.81
Continuous AAC	0.00024	0.000042	< 0.01
IL-6 (pg/mL)	0.10	0.05	0.05
Higher AAC (vs. lower AAC)				2.42	0.51	< 0.01
IL-6 within higher AAC				0.01	0.07	0.86
IL-6 within lower AAC				0.16	0.07	0.04

IL-6 was treated as a continuous variable, while AAC was treated as a continuous variable in the model without the interaction term, but dichotomized at the median in the nested model. Number of subjects with all data = 273.