Table 3.
Gene Ontology categories significantly enriched among motif-containing genes
| Motif | GO category | Description | p-value | Adjusted p-value |
| GLYCB | GO:0016530 | Metallochaperone activity | 1.00E-05 | 0.0004 |
| MICB | GO:0016530 | Metallochaperone activity | 1.00E-05 | 0.0004 |
| NTBA | GO:0022414 | Reproductive process | 1.00E-06 | 0.0001 |
| NTBA | GO:0016530 | Metallochaperone activity | 1.00E-05 | 0.0004 |
| NTBB | GO:0002376 | Immune system process | 1.00E-06 | 0.0002 |
| NTBB | GO:0009987 | Cellular process | 0.0005 | 0.0110 |
| NTBB | GO:0009055 | Electron carrier activity | 0.0025 | 0.0371 |
| NTBB | GO:0008152 | Metabolic process | 0.0026 | 0.0367 |
| NTBB | GO:0030234 | Enzyme regulator activity | 0.0030 | 0.0400 |
| RPA | GO:0045735 | Nutrient reservoir activity | 1.00E-06 | 0.0001 |
| RPA | GO:0005840 | Ribosome | 1.45E-06 | 0.0001 |
| RPA | GO:0005198 | Structural molecule activity | 3.65E-06 | 0.0002 |
| RPA | GO:0006412 | Translation | 0.0001 | 0.0039 |
| RPA | GO:0009987 | Cellular process | 0.0004 | 0.0096 |
| RPA | GO-0043226 | Organelle | 0.0005 | 0.0110 |
| RPA | GO-0032991 | Macromolecular complex | 0.0005 | 0.0107 |
| RPA | GO:0051234 | Establishment localization | 0.0008 | 0.0148 |
| RPA | GO:0051179 | Localization | 0.0008 | 0.0156 |
| RPB | GO-0044421 | Extracellular region part | 1.00E-07 | 3.52E-05 |
| RPB | GO:0022414 | Reproductive process | 1.00E-06 | 0.0001 |
| RPB | GO:0016530 | Metallochaperone activity | 1.00E-05 | 0.0003 |
| RPB | GO:0006412 | Translation | 0.0001 | 0.0020 |
| RPB | GO:0005840 | Ribosome | 0.0003 | 0.0074 |
| RPB | GO-0043226 | Organelle | 0.0010 | 0.0172 |
| RPB | GO:0009987 | Cellular process | 0.0018 | 0.0285 |
| RPB | GO:0005198 | Structural molecule activity | 0.0018 | 0.0282 |
Significantly enriched GO categories (adjusted p-value < 0.05) for motif-containing genes. The results are listed by each motif and ordered based on their Benjamini Hochberg adjusted p-value. A good correlation is observed between the functional pathways associated with the seed genes and the GO category that is over-represented in the corresponding motif-containing genome-wide gene sets in the case of motifs NTBB, RPA and RPB.