. 2009 Apr 24;10(4):R44. doi: 10.1186/gb-2009-10-4-r44

Table 5.

Enriched X. laevis pathways due to cyclopamine treatment using SEPEA_NT2

KEGG pathway ID	Pathway description	P-value
[path:xla03022]	Basal transcription factors	0.01
[path:xla04010]	MAPK signaling	0.02
[path:xla00460]	Cyanoamino acid metabolism	0.024
[path:xla00550]	Peptidoglycan biosynthesis	0.031
[path:xla02010]	ABC transporters	0.045
[path:xla03050]	Proteasome	0.05
[path:xla00982]	Drug metabolism - cytochrome P450	0.053
[path:xla00830]	Retinol metabolism	0.059
[path:xla04630]	Jak-STAT signaling	0.07
[path:xla04012]	ErbB signaling	0.1

Enriched KEGG [44] pathways (with P-value ≤ 0.1) due to cyclopamine treatment of developing X. laevis, designed to inhibit SHH signaling, using microarray data from GEO [45] [GEO:GSE8293]. P-values were obtained using the SEPEA_NT2 analysis with 1,000 randomizations to compute significance.