Fig. 1.

Inhibition of group A PAKs impairs US3-induced actin rearrangements. (A) Pictures show actin architecture in PRV-infected ST in the presence or absence of the group A PAK inhibitor IPA-3. Viral antigens are in green, and actin is in red. (Scale bar: 10 μm.) (B) Graphs show percentages of cells with cell projections (white bars) or intact actin stress fibers (black bars). *, Significant differences compared with the control at the 0.05 level. (C) Western blots show expression of viral proteins US3 and gB. Arrowheads indicate position of US3 long and short isoforms. Actin served as a loading control.