Fig. 2.

Effects of chBP2 expression in FGF2-positive SW-13 cells. (A, B) Induction of angiogenesis in a chicken embryo chorioallantoic membrane (CAM) assay. Cells were placed on a collagen gel matrix on the CAM, and neoangiogenesis was scored. The arrowheads point to newly formed vessels. (C, D) Induction of filopodia-like cellular extensions in attached cells (38). Extensions were quantitated and are indicated by arrowheads. (E) Colony formation in soft agar. Colonies >100 μm were counted. Mock- or chBP2-transfected SW-13 cells were compared in these assays. **, P < 0.01.