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. 2009 May 13;7:33. doi: 10.1186/1479-5876-7-33

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Copyright © 2009 Sarin et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Percent change in Gd-DTPA area under the time-concentration curve (AUC) of RG-2 glioma tumor tissue and temporalis skeletal muscle tissue as a result of the 15 minute intravenous infusion of normal saline or respective bradykinin B2 agonist. (A) Anterior brain RG-2 gliomas; NS (N = 6), BK (N = 8), Lys-BK (N = 8), Met-Lys-BK (N = 7), Labradimil (N = 13); (B) Posterior brain RG-2 gliomas; NS (N = 6), BK (N = 8), Lys-BK (N = 8), Met-Lys-BK (N = 7), Labradimil (N = 12); (C) Temporalis skeletal muscle, NS (N = 6), BK (N = 8), Lys-BK (N = 8), Met-Lys-BK (N = 7), Labradimil (N = 13). P-values reported are adjusted values using Dunnett-Hsu adjustments for multiple post hoc comparisons of treatment effect.