Table 1.
Cell Clonesb | Virus Isolatesc | |||
Mock | BAL | MN | US1 | |
CCRT | <15 | 331 ± 20 | 110 ± 14 | 54 ± 2 |
CCRT K4 | <15 | 33 ± 6 | 25095 ± 3191 | n.d.d |
CCRT C6 | <15 | 18477 ± 1119 | 35 ± 2 | 16635 ± 1743 |
VCRT | <15 | 142 ± 12 | 89 ± 9.5 | 46 ± 2 |
VCRT C17 | <15 | 1072 ± 37 | 106 ± 8 | 40 ± 3 |
aSupernatants of each infection experiments were tested for the presence of p24gag in duplicates at several time post infection (day 1 to 24) and the peak concentration is presented. Results represent means ± SD of at lease two experiments.
bCotton rat cell clones expressing human CD4 with CXCR4 (CCRT K4), or with CCR5 (CCRT C6 and VCRT C17).
cHIV-1 viral isolates X4-tropic (MN) and R5-tropic (BAL and US1).
d not determined.