Table 2.

Lipid profile according to LRP8 R952Q in non-diabetic subjects without lipid-lowering therapy (n = 449)

LRP8 R952Q variant	RR (n = 190)	RQ (n = 193)	QQ (n = 66)	P *
Total cholesterol (mmol/l)	5.63 ± 1.10	5.90 ± 1.15	5.68 ± 0.90	0.774
LDL-cholesterol (mmol/l)	3.75 ± 0.98	3.92 ± 1.02	3.84 ± 0.80	0.546
HDL-cholesterol (mmol/l)	1.30 ± 0.37	1.36 ± 0.39	1.27 ± 0.37	0.643
Triglyceride (mmol/l)	1.63 ± 0.83	1.74 ± 0.86	1.70 ± 0.92	0.530
Apo A-I (g/l)	1.34 ± 0.25	1.36 ± 0.26	1.31 ± 0.25	0.426
Apo B (g/l)	1.13 ± 0.29	1.18 ± 0.27	1.17 ± 0.32	0.129
Apo C-III (mg/dl)	10.9 ± 3.2	11.5 ± 3.8	11.1 ± 3.7	0.825
ApoE (g/l)	0.045 ± 0.020	0.044 ± 0.014	0.040 ± 0.008	0.047

*: by ANOVA with polynomial contrasts for linear trend