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Comparison of the human and mouse ghrelin gene. The human ghrelin gene (GHRL) contains three first 5' untranslated exons (-1, 0 and a 5' extended exon 1/5'ext) shown as blue boxes. Note that the human exon -1 can also splice into exon 0. The murine ghrelin gene (Ghrl) contains exons homologous to the human exon 0 and the 5' extended exon 1 (shown as orange boxes), but lacks exon -1. The minimum and maximum size (in base pairs) of exons is shown above each exon.
