Table 1.
Comparison of Characteristics between ESCC cases and controls (P value: Mann-Whitney U test; *chi square test; **Fisher's exact test).
| ESCC cases (N = 253) |
Controls (N = 253) |
p-value | |
|---|---|---|---|
| Patients profiles | |||
| Male/Female | 225/28 | 225/28 | >0.9999 |
| Age (median; range) | 65; 38–86 | 65; 38–86 | >0.9999 |
| BMI (median; range) | 20.9; 14.8–30.8 | 22.8; 14.5–33.1 | <0.0001 |
| Current regular drinker | 210 (83.0%) | 142 (56.1%) | <0.0001* |
| Current smoker Endoscopic findings |
205 (81.0%) | 133 (52.6%) | <0.0001* |
| GMA Open-type 2, 3 | 164 (64.8%) | 127 (50.2%) | 0.0009* |
| Hiatal hernia | 60 (23.7%) | 74 (29.2%) | 0.1584* |
| Erosive esophagitis | |||
| Total (LA-A to D) | 13 (5.1%) | 64 (25.3%) | <0.0001* |
| Mild (LA-A, B) | 12 (4.7%) | 59 (23.3%) | <0.0001* |
| Severe (LA-C, D) | 1 (0.4%) | 5 (2.0%) | 0.2160** |
| Barrett's epithelium | 80 (31.6) | 114 (45.1%) | 0.0019* |
BMI = body mass index; GMA = gastric mucosal atrophy