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. 2009 Apr 29;10:202. doi: 10.1186/1471-2164-10-202

Table 4.

Genes differentially affected by dichlorvos and fenamiphos exposure

ProbeSet WBIDa Geneb Description Biological Role Dicc Fend
191857_s_at WBGene00011462 scl-22 SCP-like extracellular protein -1.2 -3.7

189735_at WBGene00002021 hsp-17 heat shock protein Stress 2.0 -1.0

190518_at WBGene00006629 tsp-3 tetraspanin 2.5 1.0

184400_at WBGene00017726 F22H10.2 unknown 3.2 1.7

192142_at WBGene00008084 C44C10.3 major facilitator superfamily transporter Detoxification 3.6 1.4

180425_s_at WBGene00017484 F15E6.3 RRM-type RNA binding protein miRNA regulation 4.0 1.9

180592_s_at WBGene00021224 clec-209 unknown function – contains c-type lectin domain -2.1 2.0

178843_at WBGene00008584 F08G5.6 CUB domain containing protein -2.3 4.9

193604_at WBGene00007455 ugt-22 UDP-glucoronosyl and UDP-glucosyl transferases Phase 2 enzyme -1.6 6.7

183703_s_at WBGene00012788 Y43D4A.2 UDP-glucoronosyl and UDP-glucosyl transferases Phase 2 enzyme -1.4 7.9

191418_at WBGene00013901 ugt-16 UDP-glucoronosyl and UDP-glucosyl transferases Phase 2 enzyme -1.8 7.7

189394_at WBGene00019473 cyp-35A5 cytochrome P450 Phase 1 enzyme -1.1 15.9

193924_at WBGene00003997 pgp-3 P-glycoprotein 3 Detoxification 1.0 3.1

190248_s_at WBGene00004008 pgp-14 P-glycoprotein 14 Detoxification -1.1 3.3

185525_at WBGene00015399 cyp-35A1 cytochrome P450 Phase 1 enzyme 1.1 4.3

188031_s_at WBGene00006890 vem-1 putative steroid membrane receptor – involved in axon guidance 1.6 5.7

191066_s_at WBGene00013906 ugt-5 UDP-glucoronosyl and UDP-glucosyl transferases Phase 2 enzyme 2.2 5.6

188962_at WBGene00019234 ugt-8 ugt family, 7TM chemoreceptor Phase 2 enzyme 1.2 10.4

178316_at WBGene00007811 C29F7.2 unknown 2.0 9.8

188217_at WBGene00004236 ptr-22 sterol sensing domain protein – patch related Sterol trafficking 2.4 14.7

189282_at WBGene00007362 cyp-35C1 cytochrome P450 Phase 1 enzyme 1.8 54.5

189283_s_at WBGene00007362 cyp-35C1 cytochrome P450 Phase 1 enzyme 2.3 54.7

189512_at WBGene00015400 cyp-35A2 cytochrome P450 Phase 1 enzyme 3.0 33.2

a- WormBase gene identifier

b- Gene names and descriptions were derived from WormBase, release WS189 [46].

c- Gene expression fold change values for dichlorvos SVM predicted high concentration

d- Gene expression fold change values for fenamiphos high concentration