Table 4.
ProbeSet | WBIDa | Geneb | Description | Biological Role | Dicc | Fend |
191857_s_at | WBGene00011462 | scl-22 | SCP-like extracellular protein | -1.2 | -3.7 | |
189735_at | WBGene00002021 | hsp-17 | heat shock protein | Stress | 2.0 | -1.0 |
190518_at | WBGene00006629 | tsp-3 | tetraspanin | 2.5 | 1.0 | |
184400_at | WBGene00017726 | F22H10.2 | unknown | 3.2 | 1.7 | |
192142_at | WBGene00008084 | C44C10.3 | major facilitator superfamily transporter | Detoxification | 3.6 | 1.4 |
180425_s_at | WBGene00017484 | F15E6.3 | RRM-type RNA binding protein | miRNA regulation | 4.0 | 1.9 |
180592_s_at | WBGene00021224 | clec-209 | unknown function – contains c-type lectin domain | -2.1 | 2.0 | |
178843_at | WBGene00008584 | F08G5.6 | CUB domain containing protein | -2.3 | 4.9 | |
193604_at | WBGene00007455 | ugt-22 | UDP-glucoronosyl and UDP-glucosyl transferases | Phase 2 enzyme | -1.6 | 6.7 |
183703_s_at | WBGene00012788 | Y43D4A.2 | UDP-glucoronosyl and UDP-glucosyl transferases | Phase 2 enzyme | -1.4 | 7.9 |
191418_at | WBGene00013901 | ugt-16 | UDP-glucoronosyl and UDP-glucosyl transferases | Phase 2 enzyme | -1.8 | 7.7 |
189394_at | WBGene00019473 | cyp-35A5 | cytochrome P450 | Phase 1 enzyme | -1.1 | 15.9 |
193924_at | WBGene00003997 | pgp-3 | P-glycoprotein 3 | Detoxification | 1.0 | 3.1 |
190248_s_at | WBGene00004008 | pgp-14 | P-glycoprotein 14 | Detoxification | -1.1 | 3.3 |
185525_at | WBGene00015399 | cyp-35A1 | cytochrome P450 | Phase 1 enzyme | 1.1 | 4.3 |
188031_s_at | WBGene00006890 | vem-1 | putative steroid membrane receptor – involved in axon guidance | 1.6 | 5.7 | |
191066_s_at | WBGene00013906 | ugt-5 | UDP-glucoronosyl and UDP-glucosyl transferases | Phase 2 enzyme | 2.2 | 5.6 |
188962_at | WBGene00019234 | ugt-8 | ugt family, 7TM chemoreceptor | Phase 2 enzyme | 1.2 | 10.4 |
178316_at | WBGene00007811 | C29F7.2 | unknown | 2.0 | 9.8 | |
188217_at | WBGene00004236 | ptr-22 | sterol sensing domain protein – patch related | Sterol trafficking | 2.4 | 14.7 |
189282_at | WBGene00007362 | cyp-35C1 | cytochrome P450 | Phase 1 enzyme | 1.8 | 54.5 |
189283_s_at | WBGene00007362 | cyp-35C1 | cytochrome P450 | Phase 1 enzyme | 2.3 | 54.7 |
189512_at | WBGene00015400 | cyp-35A2 | cytochrome P450 | Phase 1 enzyme | 3.0 | 33.2 |
a- WormBase gene identifier
b- Gene names and descriptions were derived from WormBase, release WS189 [46].
c- Gene expression fold change values for dichlorvos SVM predicted high concentration
d- Gene expression fold change values for fenamiphos high concentration