Table 1.

Echocardiographic left ventricular functional and morphologic parameters in transgenic mice

Strain	Heart rate, beats per minute	Fractional shortening, %	End systolic dimension, mm	End diastolic dimension, mm	Septal wall thickness, mm	Posterior wall thickness, mm	Left ventricular mass, mg	n
NTG	470 ± 30	50 ± 1	1.7 ± 1	3.4 ± 2	0.41 ± 0.01	0.40 ± 0.01	65 ± 4	7
Gαq	288 ± 17∗	32 ± 2	2.5 ± 1∗	4.0 ± 0.1	0.42 ± 0.01	0.42 ± 0.01	90 ± 3∗	5
Gαq/βARKmini	282 ± 22∗	27 ± 1∗	2.8 ± 0.1∗	4.1 ± 0.1	0.41 ± 0.01	0.40 ± 0.01	91 ± 4∗	6
Gαq/βARL	348 ± 18†	44 ± 2†	2.1 ± 0.1	3.7 ± 0.1	0.40 ± 0.01	0.41 ± 0.01	74 ± 1†	5

HR, heart rate; FS, fractional shortening; ESD, end systolic dimension; EDD, end diastolic dimension; SWT, septal wall thickness; PWT, posterior wall thickness; LV mass, left ventricular mass. ∗ = P < 0.05 vs NTG.  

^† = P < 0.05 vs Gαq (n = 5–11 per group).