Table 6.

Comparison of the differential expressions of genes detected in our study with those previously reported¹⁷.

Gene	Differential Expression*	Differential Expression**	Description
LILRB1	↓	↓	Leukocyte immunoglobulin-like receptor, subfamily A
C9orf47	↓	↓	Endo differentiation, sphingolipid G-protein-coupled receptor, 3
NRN1	↓	↓	Homo sapiens neuritin
PLCB4	↓	↓	Phospholipase C, beta 4
GATA6	↓	↓	Homo sapiens mRNA for GATA-6
THY1	↓	↓	Thy-1 cell surface antigen
LRRC15	↓	↓	Leucine-rich repeat containing 5
MAB21L2	↑	↑	Homo sapiens MAB21L2 protein
CES1	↑	↑	Carboxylesterase
SFRP2	↑	↑	Secreted frizzled-related protein 2
SEMA3A	↓	↑	Sema domain, immunoglobulin domain (Ig), (semaphorin) 3A
SFRP1	↓	↑	Secreted frizzled-related protein 1
LMO2	↓	↑	LIM domain only 2
CRLF1	↓	↑	Cytokine receptor-like factor 1
TMOD1	↓	↑	Homo sapiens, tropomodulin
PRG4	↓	↑	Proteoglycan 4
HLA-DQA1	↑	↓	MHC class II, DQ alpha 1
HLA-DRA	↑	↓	MHC class 22 HLA-DR-alpha
HLA-DRB4	↑	↓	MHC class II DR beta 4
CTSC	↑	↓	Cathepsin C
TBX5	↑	↓	ESTs, AW269421
HOXD13	↑	↓	Homeo box D13
BST1	↑	↓	Bone marrow stromal cell antigen 1

^*This study.

^**Previously reported¹⁷.

↑ indicates elevated expression in hTERT-OA 13A FLS (passage 25) compared to hTERT-RA 516 FLS (passage 25) or in primary OA FLS (passage 2−3) compared to primary RA FLS (passages 2−3). ↓ indicates decreased expression in hTERT-OA 13A FLS (passage 25) compared to hTERT-RA 516 FLS (passage 25) or in primary OA FLS (passages 2−3) compared to primary RA FLS (passages 2−3).