Figure 3. Forearm hyperaemic responses to mild rhythmic handgrip exercise before and during ascorbic acid infusion.

Prior to ascorbic acid, absolute forearm blood flow tended to be lower in older vs. young adults during mild intensity steady-state exercise (A; *P = 0.06–0.09 for minutes 1–6). When expressed as percentage increases from baseline, forearm hyperaemic responses were significantly reduced in older adults (B; *P < 0.05 for minutes 1–10). Infusion of ascorbic acid significantly increased forearm blood flow in older, but not young adults during continued exercise. †P < 0.05 vs. steady-state exercise within older group for minutes 7–15.