Figure 9. Relationship between lamina I spinoparabrachial activity and behaviour.

The discharge evoked by a 10 s duration 42°C heat stimulus has been plotted against the difference in heat-evoked withdrawal latency between the ipsilateral and contralateral hindpaws. Paw withdrawal latency difference was a significant co-variant in the heat-evoked stimulus–response curves of animals with a CCI when compared to sham-operated controls (P < 0.03, ANCOVA). As withdrawal latency differences for unoperated controls were not measured they have been assigned to zero for convenience.