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. 2009 Apr 3;26(7):1679–1688. doi: 10.1007/s11095-009-9878-2

Fig. 2.

Fig. 2

Degradation of oxytocin over time at 40°C (A), 55°C (B), 70°C (C) and 80°C (D) for formulations with 0.1 mg/ml oxytocin at pH 2.0, 4.5, 7.0 and 9.0 determined by RP-HPLC. Linear fitting (where r2 > 0.99) showed the first order kinetics, with the slope of the resulting straight lines representing the degradation rate constant, kobs.