Table 1.
Basal | Treatment | Recovery | |
---|---|---|---|
CAP | 119 ± 6 | 118 ± 7 | 118 ± 6 |
CAPZ+CAP | 125 ± 2 | 125 ± 2 | 124 ± 2 |
RP67580+CAP | 124 ± 3 | 124 ± 2 | 121 ± 2 |
L703, 606+CAP | 121 ± 6 | 122 ± 5 | 125 ± 5 |
CGRP8-37+CAP | 124 ± 3 | 122 ± 3 | 120 ± 4 |
SP | 121 ± 5 | 120 ± 5 | 118 ± 4 |
CAPZ+SP | 120 ± 4 | 120 ± 3 | 119 ± 4 |
CGRP | 117 ± 5 | 118 ± 6 | 118 ± 5 |
CAPZ+CGRP | 120 ± 4 | 123 ± 4 | 120 ± 4 |
Value was expressed as mean ± SE, n=5–7 in each group
CAP, Capsaicin CAPZ, Capsazepine, TRPV1 antagonist
RP67580, NK1 antagonist L703,606, NK1 antagonist
CGRP8-37, CGRP receptors antagonist SP, Substance P
CGRP, Calcitonin gene-related peptide