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. 2008 Feb 21;14(7):1044–1052. doi: 10.3748/wjg.14.1044

Table 1.

Semi-quantitative analysis of Snail, Slug and Twist in malignant progression of Barrett’s metaplasia to adenocarcinoma (Immunoreactivity score)

S BM (-ve) BM (+ve) ADC
Snail 2.4 2.5 2.9 8.7a
Slug 6.7 2.6 3.5 10.5ac
Twist 4.5 4.7 5.2 7.1

Semi-quantitative analysis of immunoreactivity for Snail, Slug and Twist in specimens of squamous esophagus (S); Intestinal type Barrett’s metaplasia without associated adenocarcinoma BM (-ve), intestinal Barrett’s metaplasia with associated adenocarcinoma BM (+ve) and esophageal adenocarcinoma (ADC). The mean staining scores were calculated for each type of mucosa and the mean fold change in protein expression was calculated.

a

denotes significant (P < 0.05) differences between adenocarcinoma and intestinal type Barrett’s metaplasia without associated adenocarcinoma.

c

denotes significant (P < 0.05) differences between adenocarcinoma and intestinal type Barrett’s metaplasia with associated adenocarcinoma.