Table 4.
Optimal choice of catheter under uncertainty, given different data scenarios
Scenario | Optimal catheter choice | Incremental outcomes with no uncertainty | Average incremental monetary net benefits given uncertaintyb | |||
Catheter type | Probability of error | Costsa | QALYsa | Mean | 95% Confidence interval | |
Baseline | MR | 0.62 | - $130,289 | 1.64 | 948 | -106 to 3,792 |
Low bed day ($335 ICU/$101 ward) | MR | 0.76 | + $28,257 | 1.64 | 191 | -348 to 1,317 |
High mortality (15%) | MR | 0.46 | - $106,223 | 26.65 | 2,441 | 116 to 8,516 |
No utility weights used | MR | 0.62 | - $130,289 | 2.33 | 1,042 | -166 to 3,961 |
Increased length of stay (6.5 days ICU/6 days ward) | MR | 0.56 | - $282,038 | 1.64 | 1,239 | -57 to 4,795 |
Low infection rate (0.8%) | MR | 0.75 | - $1,972 | 0.53 | 325 | -71 to 1,283 |
High infection rate (5.0%) | MR | 0.56 | - $314,400 | 3.23 | 1,725 | -139 to 6,455 |
aRelative to uncoated catheters and per 1,000 catheters; bMonetary net benefits reported per catheter relative to uncoated catheters assuming a willingness-to-pay for a QALY of AUD $40,000.
ICU, intensive care unit; QALY, quality-adjusted life year.