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. 2009 Mar 30;13(2):R43. doi: 10.1186/cc7766

Table 2.

Comparison of NSAID and aspirin use by cases versus controls

Analysis NSAID users (%) OR (95% CI) P value

Cases Controls
Global (n = 152)a NSAIDs and aspirin 27 28 0.93 (0.52 to 1.64) 0.79
NSAIDs 24 21 1.18 (0.64 to 2.19) 0.56
 Chronic treatment 4 5 0.86 (0.24 to 2.98) 0.78
 Acute treatment 20 16 1.40 (0.69 to 2.92) 0.32
Aspirin 5 10 0.47 (0.16 to 1.22) 0.09

Subgroup analysis Diabetes (n = 20)a
 NSAIDs 20 5 4.00 (0.40 to 196.99) 0.18
 Aspirin 10 5 2.00 (0.40 to 196.99) 0.56
No diabetes (n = 132)a
 NSAIDs 24 23 1.05 (0.55 to 2.00) 0.88
 Aspirin 4 11 0.36 (0.10 to 1.05) 0.04b
Site of infection: lung (n = 71)a
 NSAIDs 14 15 0.90 (0.32 to 2.46) 0.82
 Aspirin 7 11 0.63 (0.16 to 2.17) 0.40
Site of infection: urinary tract (n = 30)a
 NSAIDs 27 30 0.83 (0.02 to 3.28) 0.76
 Aspirin 3 7 0.50 (0.01 to 9.60) 0.56
Site of infection: skin and soft tissue (n = 16)a
 NSAIDs 31 31 1.00 (0.07 to 13.80) 1.00
 Aspirin 0 6 - - -
Site of infection: other (n = 35)a
 NSAIDs 37 20 2.50 (0.72 to 10.92) 0.11
 Aspirin 3 11 0.25 (0.01 to 2.53) 0.18

aThe n values indicate the number of pairs. bThe apparent discordance between the confidence interval (CI) and statistical test results is due to the use of different but asymptotically equivalent statistical methods. NSAID, nonsteroidal anti-inflammatory drug; OR, odds ratio.