Table 2.
Analysis | NSAID users (%) | OR (95% CI) | P value | ||
Cases | Controls | ||||
Global (n = 152)a | NSAIDs and aspirin | 27 | 28 | 0.93 (0.52 to 1.64) | 0.79 |
NSAIDs | 24 | 21 | 1.18 (0.64 to 2.19) | 0.56 | |
Chronic treatment | 4 | 5 | 0.86 (0.24 to 2.98) | 0.78 | |
Acute treatment | 20 | 16 | 1.40 (0.69 to 2.92) | 0.32 | |
Aspirin | 5 | 10 | 0.47 (0.16 to 1.22) | 0.09 | |
Subgroup analysis | Diabetes (n = 20)a | ||||
NSAIDs | 20 | 5 | 4.00 (0.40 to 196.99) | 0.18 | |
Aspirin | 10 | 5 | 2.00 (0.40 to 196.99) | 0.56 | |
No diabetes (n = 132)a | |||||
NSAIDs | 24 | 23 | 1.05 (0.55 to 2.00) | 0.88 | |
Aspirin | 4 | 11 | 0.36 (0.10 to 1.05) | 0.04b | |
Site of infection: lung (n = 71)a | |||||
NSAIDs | 14 | 15 | 0.90 (0.32 to 2.46) | 0.82 | |
Aspirin | 7 | 11 | 0.63 (0.16 to 2.17) | 0.40 | |
Site of infection: urinary tract (n = 30)a | |||||
NSAIDs | 27 | 30 | 0.83 (0.02 to 3.28) | 0.76 | |
Aspirin | 3 | 7 | 0.50 (0.01 to 9.60) | 0.56 | |
Site of infection: skin and soft tissue (n = 16)a | |||||
NSAIDs | 31 | 31 | 1.00 (0.07 to 13.80) | 1.00 | |
Aspirin | 0 | 6 | - - | - | |
Site of infection: other (n = 35)a | |||||
NSAIDs | 37 | 20 | 2.50 (0.72 to 10.92) | 0.11 | |
Aspirin | 3 | 11 | 0.25 (0.01 to 2.53) | 0.18 |
aThe n values indicate the number of pairs. bThe apparent discordance between the confidence interval (CI) and statistical test results is due to the use of different but asymptotically equivalent statistical methods. NSAID, nonsteroidal anti-inflammatory drug; OR, odds ratio.