Fig. 6.
Suppressed ERK activation in the tub/tub mice and the SF-protective effect. (A) Representative Western blots; (B) measurements of p-ERKs (activated ERK). CBB was used as the control. The total ERKs are also presented, showing no or less change with the treatment. SF treatment: daily intraperitoneally injection with SF (50 mg/kg in PBS) or PBS alone for 20 days from P10. The cochleae were harvested at P60 and P90. The measurements are expressed as mean ± S.D. (n = 4 in each group). *p < 0.05; **p < 0.01.