Table 2.

Unadjusted response variables according to ethnicity and ADRA2C del322-325 and GNB3 genotypes

	Ethnicity			ADRA2C del322-325 genotype			GNB3 C/T genotype
	White subjects	Black Subjects	P- value	Ins/Ins or Ins/Del	Del/Del	P- value	CC or CT	TT	P- value
Δ Heart rate (bpm)	11.6± 8.4	20.0 ± 14.0	0.002	13.4 ± 9.7	30.9 ± 15.8	0.004	12.1 ± 9.5	20.4 ± 13.8	0.003
Δ Systolic BP (mmHg)	18.2 ± 9.2	22.2 ± 15.2	0.16	18.8 ± 12.1	28.6 ± 13.3	0.016	18.1 ± 11.4	22.8 ± 13.8	0.10
Δ Diastolic BP (mmHg)	14.1 ± 7.3	15.3 ± 11.3	0.56	13.9 ± 9.2	19.7 ± 10.0	0.058	13.6 ± 8.8	15.8 ± 10.2	0.29
Δ Plasma norepinephrine (pg/mL)	100.5 ± 109.5	76.2 ± 80.6	0.28	91.5 ± 101.8	71.3 ± 55.8	0.35	97.8 ± 107.8	76.4 ± 81.9	0.35
Δ Plasma epinephrine (pg/mL)	6.7 ± 12.3	13.9 ± 18.0	0.13	8.9 ± 14.3	19.7 ± 21.9	0.22	9.8 ± 16.5	10.7 ± 14.9	0.74

P-values refer to the comparison between white and black subjects or the comparison between the genotype groups.