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. 2009 Jun 9;3(6):e455. doi: 10.1371/journal.pntd.0000455

Figure 1. Gene conversion between TbrPDEB1 and TbrPDEB2 in the region coding for the GAF-A domain.

Figure 1

Panel A: B1: DNA sequence of TbrPDEB1 (nucleotides 720–1139 of the open reading frame of TbrPDEB1); B2a: DNA sequence of the wild-type allele of TbrPDEB2; B2b: DNA sequence of the allele having undergone gene conversion with TbrPDEB1. Open circles, bold, underlined: nucleotide changes due to the conversion event; shaded: polypyrimidine stretches before and after converted segment. Panel B: corresponding amino acid sequences (amino acids 241–420 of TbrPDEB1). Closed circles, bold, underlined: amino acid substitutions due to the conversion event; shaded: GAF-A domain.