Table 2. Results of linkage analysis of 28 microsatellite markers spanning the SPA2 locus.
| Marker | Genetic location (cM) | Physical location (bp) | Zlr | nominal P | Information content |
| D9S1677 | 112.9 | 110,977,411–110,977,668 | 2.38 | 8.68×10−3 | 0.97 |
| D9S160 | 113.2 | 111,418,819–111,418,976 | 2.47 | 6.84×10−3 | 0.97 |
| D9S1675 | 114.4 | 112,128,955–112,129,173 | 2.34 | 9.68×10−3 | 0.99 |
| D9S1854 | 114.4 | 112,149,837–112,150,087 | 2.34 | 9.69×10−3 | 0.99 |
| D9S1828 | 114.4 | 112,372,536–112,372,710 | 2.34 | 9.69×10−3 | 0.99 |
| D9S1683 | 115.1 | 112,903,157–112,903,331 | 2.19 | 1.41×10−2 | 0.99 |
| D9S1880 | 115.1 | 113,085,561–113,085,752 | 2.19 | 1.41×10−2 | 0.99 |
| D9S279 | 118.8 | 115,267,469–115,267,714 | 2.78 | 2.68×10−3 | 0.96 |
| D9S1824 | 120.1 | 115,931,926–115,932,043 | 3.20 | 6.94×10−4 | 0.96 |
| D9S1855 | 121.3 | 116,550,769–116,550,989 | 2.90 | 1.89×10−3 | 0.99 |
| D9S155 | 121.4 | 116,938,283–116,938,406 | 2.65 | 3.98×10−3 | 1.00 |
| D9S1776 | 121.4 | 116,999,255–116,999,373 | 2.66 | 3.97×10−3 | 1.00 |
| D9S177 | 121.5 | 116,999,255–116,999,373 | 2.79 | 2.63×10−3 | 1.00 |
| D9S170 | 123.0 | 118,107,200–118,107,315 | 2.51 | 6.11×10−3 | 0.99 |
| D9S154 | 123.0 | 118,380,667–118,380,844 | 2.62 | 4.37×10−3 | 0.99 |
| D9S1802 | 123.3 | 118,663,193–118,663,409 | 2.67 | 3.80×10−3 | 0.98 |
| D9S1811 | 123.9 | 119,261,235–119,261,616 | 2.67 | 3.79×10−3 | 0.98 |
| D9S1864 | 125.4 | 119,526,784–119,527,053 | 2.52 | 5.81×10−3 | 0.98 |
| D9S275 | 126.6 | 120,626,197–120,626,394 | 2.43 | 7.58×10−3 | 0.97 |
| D9S1872 | 128.4 | 120,829,322–120,829,427 | 2.29 | 1.11×10−2 | 0.99 |
| D9S195 | 128.4 | 121,169,236–121,169,435 | 2.43 | 7.65×10−3 | 0.99 |
| D9S1682 | 130.9 | 124,033,006–124,033,207 | 2.60 | 4.67×10−3 | 0.96 |
| D9S1881 | 134.5 | 126,019,300–126,019,529 | 3.07 | 1.09×10−3 | 0.98 |
| D9S1825 | 135.1 | 126,927,953–126,928,083 | 3.03 | 1.24×10−3 | 0.99 |
| D9S1829 | 135.2 | 127,814,464–127,814,679 | 3.03 | 1.23×10−3 | 0.98 |
| D9S1798 | 135.8 | 128,212,217–128,212,457 | 2.96 | 1.54×10−3 | 0.98 |
| D9S1821 | 136.2 | 128,369,402–128,369,573 | 2.97 | 1.47×10−3 | 0.98 |
| D9S112 | 136.8 | 128,413,136–128,413,266 | 2.91 | 1.80×10−3 | 0.97 |
Analysis was carried out in 149 independent families with multiple cases of spondyloarthritis. Three markers previously studied in a subset of 120 of these families appear in bold [13]. Markers were placed according to ENSEMBL database. Zlr statistics were calculated by multipoint analysis with ALLEGRO program. Markers within frames are those for which positive linkage was detected with P<0.05, after correction for multiple testing.