Table 5. Clinical characteristics of patients with spondyloarthritis included in the whole study.a .
| Characteristics | Familial patients (n = 711) | Singleton cases (n = 371) |
| Age in year, mean±SD | 44±0.56 | 46±0.70 |
| Age at onset, in year, mean±SD | 24±0.36 | 26±0.60 |
| Sex ratio, men∶women | 383∶328 | 177∶194 |
| HLA-B27 positivityb | 93% | 77% |
| Axial manifestations | ||
| Back/buttock pain | 97% | 97% |
| Sacroiliitis (radiography)c | 58% | 50% |
| Peripheral manifestations | ||
| Arthritis | 43% | 35% |
| Enthesistis | 66% | 80% |
| Extra-articular manifestations | ||
| Uveitis | 29% | 23% |
| Psoriasis | 25% | 29% |
| Inflammatory bowel disease | 7% | 7% |
| Spondyloarthritis subtype | ||
| AS | 58.30% | 48.03% |
| uSpA | 29.66% | 34.05% |
| PsA | 8.96% | 16.13% |
| AIBD | 2.64% | 3.23% |
| ReA | 0.44% | / |
a
The registered manifestations correspond to those present at time of examination, or retrieved from past-medical history. Inflammatory bowel disease: Crohn's disease or ulcerative colitis; AS: ankylosing spondylitis, uSpA: undifferentiated spondyloarthritis; PsA: psoriatic arthritis; AIBD: inflammatory bowel disease-associated arthritis; ReA: reactive arthritis.
b
The number of patients evaluated in each group was 710 and 327 respectively.
c
Refers to radiographic sacroiliitis≥grade II bilateral or grade III unilateral. The number of patients evaluated in each group was 643 and 282 respectively.