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Characteristic lipid inclusions in 80-wk-old α-Gal A −/0 mice. (A) A hepatocyte containing many lipid inclusions (arrows). (B) A Kupffer cell with a large lipid inclusion (arrow). (C) The smooth muscle cells (SM) surrounding this blood vessel (L, lumen of the vessel) in the brain contain many lipid inclusions (arrows). (D) A large lipid inclusion (arrow) in an endothelial cell from a kidney sample. (Bar = 1 μm.)
