Fig. 8.
Effect of peptides infusion on amino acid concentrations in the striatum. Changes, recorded at 10-min intervals, in DOPAC, dopamine, HVA, glutamate (GLU), and GABA concentrations during the delivery (—) of 10−4 m peptides PENK 239–260 or PENK 114–133 through the dialysis probe. Results are expressed as percentage of base line. Each error bar corresponds to the standard error of the mean. Asterisks indicate statistically significant changes (*, p < 0.05; **, p < 0.01; ***, p < 0.005) in analysis of variance and Fisher's post hoc least significant difference test for comparisons with the base line. Each point is the mean value obtained from three to four animals.