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. 2009 Mar 5;150(6):2906–2914. doi: 10.1210/en.2008-1575

Figure 4.

Figure 4

The ovaries of 17NF transgenic mice exhibit more apoptotic follicles than WT controls, as assessed by TUNEL assay. A, WT ovary. B, 17NF ovary. Bars, 300 μm. C, Example of follicle from a WT ovary showing some TUNEL-positive granulosa cells. D, Typical atretic follicle from a 17NF ovary exhibiting numerous TUNEL-positive granulosa cells. E, Another example of granulosa cell apoptosis in a 17NF ovary. Bars, 100 μm. F, Ovaries from 17NF mice have a similar number of healthy antral follicles but more antral apoptotic follicles than WT ovaries. **, P < 0.01 (t test).