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. 2009 Mar 11;296(5):R1445–R1454. doi: 10.1152/ajpregu.00095.2008

Fig. 5.

Fig. 5.

Change in body weight from the first day of stress (left) and adrenal weight (right) for BHR (top) and WKY rats (bottom). Control rats, treated with either a DHB sham pellet or subcutaneous Mif pellet, are shown in solid lines and symbols or solid black bars. DHB Mif-treated rats are shown in dashed lines and open symbols or striped bars. Chronically stressed rats were exposed to repeated restraint, while acutely stressed rats were restrained only on the final day of the experiment. sP ≤ 0.05 for main effect of chronic compared with acute stress; mP ≤ 0.05 for main effect for control compared with DHB Mif treatment; *P ≤ 0.05 for a difference between BHR and WKY rats (i.e., effect of strain). The number of animals per group is as follows: acute stress control: WKY = 12, BHR = 16; acute stress Mif: WKY = 7, BHR = 10; chronic stress control: WKY = 18, BHR = 20; chronic stress Mif: WKY = 9/8 (body wt/adrenal wt), BHR = 10/9 (body wt/adrenal wt).