Table 1.
Average baseline mean arterial pressure and heart rate
| Control | Mifepristone | |||
|---|---|---|---|---|
| Mean Arterial Pressure, mmHg | ||||
| WKY acute stress | 110±2 (n= 11) | 115±4 (n=7) | ||
| WKY chronic stress | 109±1 (n=18) | 104±2 (n=7) | ||
| BHR acute stress | 122±2*(n=16) | 125±3*(n=9) | ||
| BHR chronic stress | 121±3*(n=17) | 123±4*(n=9) | ||
| Heart Rate, beats/min | ||||
| WKY acute stress | 312±6 (n=11) | 322±12 (n=7) | ||
| WKY chronic stress | 320±5 (n=18) | 295±9†(n=7) | ||
| BHR acute stress | 295±7*(n=16) | 305±5*(n=9) | ||
| BHR chronic stress | 293±7*(n=17) | 292±5*(n=9) | ||
Values are mean ± SE.
*
P < 0.05 for an overall effect of strain; mean arterial pressure was higher and heart rate lower in borderline hypertensive rats (BHR) compared with Wistar-Kyoto (WKY) rats.
†
P < 0.05 for effect of mifepristone to reduce heart rate selectively in chronically stressed WKY rats.