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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Biol Psychol. 2009 Mar 28;81(3):144–152. doi: 10.1016/j.biopsycho.2009.03.005

Table 3.

Influence of SLC6A3 and COMT genotypes on neural activation in regions of interest during inhibition

MNI coordinates
Region Side x y z t Pcorr voxels

Genotype Contrast
SLC6A3 StopInhibit—Go

STN R 10 −12 −8 2.86 0.031 6
SMA R 8 −20 72 4.46 0.003 450

COMT StopInhibit—Go

IFG (pars opercularis) R 56 14 26 4.34 0.000 781

COMT Go—Fixation

IFG (pars opercularis) R 48 10 0 5.17 0.000 977
STN R 12 −10 −2 4.18 0.020 23
Pre-SMA R 4 6 48 6.88 0.000 1,315
Globus pallidus R 16 4 −2 2.93 0.026 18

COMT StopInhibit—Fixation

IFG (pars opercularis) R 38 8 14 5.08 0.000 1,783
STN R 12 −16 −4 3.93 0.019 23
Pre-SMA R 8 6 46 6.51 0.000 1,297
Globus pallidus R 16 4 −2 4.69 0.025 21

Note. Region of interest analyses surviving a p < 0.05 small-volume correction. x, y, and z coordinates are shown in MNI space. MNI, Montreal Neurological Institute; Pcorr, corrected cluster-level p-value; IFG, inferior frontal gyrus; STN, subthalamic nucleus; SMA, supplementary motor area; R, right; N =42.