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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Biol Psychol. 2009 Mar 28;81(3):144–152. doi: 10.1016/j.biopsycho.2009.03.005

Table 4.

Genotype group differences in neural activation during inhibition

Genotype Contrast Group (N)

Region Mean Percent Signal Change (SEM)
SLC6A3 StopInhibit—Go 10/10 (26) 9+ (16)
 IFG 0.064 (0.014) 0.074 (0.016)
 STN 0.021 (0.012) 0.057 (0.020)
 SMA 0.004 (0.011) 0.043 (0.012)
 GP 0.047 (0.015) 0.082 (0.028)

COMT StopInhibit—Go v/v (10) v/m (26) m/m (6)
 IFG 0.073 (0.026) 0.074 (0.011) 0.034 (0.033)
 STN 0.034 (0.025) 0.044 (0.014) -0.002 (0.021)
 SMA 0.027 (0.015) 0.022 (0.012) -0.007 (0.021)
 GP 0.057 (0.00) 0.063 (0.000) 0.054 (0.000)

COMT Go—Fixation v/v (10) v/m (26) m/m (6)
 IFG -0.021 (0.043) 0.044 (0.016) 0.061 (0.053)
 STN 0.025 (0.035) 0.042 (0.017) 0.074 (0.032)
 SMA 0.049 (0.039) 0.110 (0.015) 0.102 (0.017)
 GP 0.002 (0.052) 0.058 (0.020) 0.096 (0.033)

COMT StopInhibit—Fixation v/v (10) v/m (26) m/m (6)
 IFG 0.052 (0.029) 0.118 (0.016) 0.094 (0.085)
 STN 0.059 (0.031) 0.086 (0.020) 0.072 (0.042)
 SMA 0.076 (0.033) 0.132 (0.016) 0.095 (0.035)
 GP 0.059 (0.036) 0.121 (0.022) 0.149 (0.044)

Note. Region of interest analyses thresholded at p < 0.01 uncorrected voxel level and percent signal change extracted. IFG, inferior frontal gyrus; STN, subthalamic nucleus; SMA, supplementary motor area; GP, globus pallidus; N =42.