Table 2.
Characteristics of randomly assigned patients in included trials
| Characteristic | TIMI IIIB | FRISC II | TACTICS-TIMI 18 | VINO | ICTUS |
|---|---|---|---|---|---|
| No. randomly assigned | 1473 | 2457 | 2220 | 131 | 1200 |
| Age (yr; mean) | 59 | 66a | 62 | 66 | 62a |
| Men (n [%]) | 972 (66) | 1708 (70) | 1463 (66) | 80 (61) | 880 (73) |
| White race (n [%]) | 1178 (80) | NA | 1722 (78) | NA | NA |
| Diabetes (n [%])† | 114 (8) | 299 (12) | 613 (28) | 33 (25) | 166 (14) |
| Previous MI (n [%]) | 604 (41) | 546 (22) | 866 (39) | 34 (26) | 278 (23) |
| MI at randomization (n [%]) | 471 (32) | 1348 (58) | 826 (37) | 131 (100) | 1200 (100) |
| ST-segment changes (n [%]) | 486 (33) | 1114 (46) | 852 (39) | 61 (47) | 474 (48) |
| T-wave inversion (n [%]) | 678 (46) | 871 (36) | 203 (9) | NA | NA |
| Thrombolytic therapy (n [%]) | 729 (49) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Percutaneous revascularization during initial hospitalization (routine angiography/selective angiography; %) | 37/23 | 42/7 | 37/23 | 47/3 | 60/28 |
| CABG during initial hospitalization (routine angiography/selective angiography; %) | 24/18 | 34/7 | 20/13 | 25/3 | 16/11 |
| Percutaneous revascularization at end of follow-up (routine angiography/selective angiography; %) | 38/26 | 43/18 | 42/29 | 52/13 | 61/40 |
| CABG at end of follow-up (routine angiography/selective angiography; %) | 25/24 | 35/19 | 22/16 | 35/30 | 18/14 |
| Mortality, (routine angiography/selective angiography; %) | 2.4/2.5 | 7.8/10.1 | 3.3/3.5 | 3.1/13.4 | 2.5/2.5 |
a
Median. Information on diabetes was available for only 782 of 1473 patients in TIMI IIIB.