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. 2009 Jun;20(6):1359–1367. doi: 10.1681/ASN.2008080842

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Copyright © 2009 by the American Society of Nephrology

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Figure 4. — mRNA abundance of individuals with over- or under- transmitted/observed haplotypes. mRNA levels of the TRAC are measured by the real-time quantitative PCR. Haplotype 1 + 3 denotes individuals homozygous for the overtransmitted/observed haplotypes 1 (GT) and 3 (GCGAGT), and haplotype 2 + 4 denotes individuals homozygous for the undertransmitted/observed haplotypes 2 (AC) and 4 (ATAGAC). Individuals (n = 8) with overtransmitted/observed haplotypes demonstrate a lower level of the TRAC mRNA than those (n = 6) with undertransmitted/observed haplotypes (P < 0.001, by t test).