Table 1.

Single SNP analysis of SNP 1–8 in 704 cases and 704 controls^a

SNP	Genotype	OR (95% CI)b	Global Pc	Corrected Pd
SNP 1	GG	1.37 (0.94–2.00)	1.3 × 10−6	1.1 × 10−5
(rs943887)	AG	0.88 (0.60–1.29)
	AA	Reference
SNP 2	TT	1.60 (1.18–2.17)	2.0 × 10−5	1.6 × 10−4
(rs943888)	CT	1.17 (0.90–1.52)
	CC	Reference
SNP 3	GG	1.36 (0.97–1.91)	0.0014	0.0110
(rs56131962)	AG	0.97 (0.70–1.36)
	AA	Reference
SNP 4	CC	1.37 (0.97–1.93)	0.0009	0.0069
(rs55766725)	CT	0.97 (0.69–1.35)
	TT	Reference
SNP 5	GG	1.40 (1.00–1.96)	0.0008	0.0067
(rs1263648)	AG	0.99 (0.71–1.37)
	AA	Reference
SNP 6	AA	1.34 (0.96–1.88)	0.0011	0.0089
(rs1263649)	AG	0.95 (0.69–1.32)
	GG	Reference
SNP 7	GG	0.89 (0.58–1.37)	0.0096	0.0745
(rs1263650)	AG	0.71 (0.46–1.10)
	AA	Reference
SNP 8	TT	1.02 (0.67–1.55)	0.0088	0.0680
(rs1263651)	CT	0.79 (0.52–1.21)
	CC	Reference

^aData for single nucleotide polymorphisms (SNPs) 1 and 2 were missing in eight individuals, and SNP 3–8 data (located in the same PCR product) were missing in three individuals in the patient group. There were no missing genotype data in the control group.

^bOdds ratio (OR) values after adjusting for age and gender by logistic regression.

^cAfter adjusting for age and gender by logistic regression, calculated by the likelihood ratio chi-square test (using genotype data), which compares the model with the marker and the model without the marker.

^dAfter Bonferroni correction for multiple testing.